Blood brain barrier in Radiology
- Why do brain pathologies enhance on Gd MRI: Contrast will not leak into the brain until the Blood brain barrier is damaged. Enhancement is seen when a CNS tumor destroys the BBB.
- Extra-axial tumors such as meningiomas and schwannomas are not derived from brain cells and do not have a blood-brain barrier. Therefore they will enhance.
- In gliomas - like astrocytomas, oligodendrogliomas and glioblastoma multiforme - enhancement usually indicates a higher degree of malignancy.
- Gangliogliomas and pilocytic astrocytomas are the exceptions to this rule: they are low-grade tumors, but they enhance vividly.
Blood brain barrier in Radiology Reviewed by Sumer Sethi on Monday, May 12, 2014 Rating: