This is 11 year old girl with seizure disorders. MRI shows presence of asymmetrical enlargement of right cerebral hemisphere relative to left with thickening of gyri, which suggests possibility of congenital hemimegalencephaly. Hemimegalencephaly is a rare congenital disorder of cortical formation with hamartomatous overgrowth of part of all of a cerebral hemisphere. This results from either increased proliferation or decreased apoptosis (or both) of developing neurons. Case submitted by Dr Swati Shah, FRCR.
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