Many tumors involving the axial skeleton can be expansile, have low signal intensity on T1-weighted images and high signal intensity on T2-weighted images, and involve the entire vertebral body. These imaging characteristics are nonspecific. Minibrain appearance has been found characteristic of Plasmacytoma. The characteristic appearance of thickened cortical struts is probably a result of a stress phenomenon from the lytic process of the plasmacytoma forcing the remainder of the bone to increase thickness as a compensatory response to weakening bone.
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