MR Spectroscopy in Meningioma
MR spectroscopy may provide additional information in cases in which the differential diagnosis
of tumors by neuroimaging is difficult. Cho reflects membrane turnover, correlates with malignancy in astrocytic tumors, and forms high peaks in meningioma. The most common proton spectrum found in meningiomas is a high Cho peak with low or absent NAA and Cr and variable amounts of lactate. Most important, an unusually high ratio of Ala to Cr has been found in meningiomas because of the high Ala and low Cr content, and this is a relatively specific finding for meningioma. Alanine is seen as doublet centered at 1.47 ppm and inverts on the long-TE sequence.
Reference- AJNR Am J Neuroradiol 20:882–885, May 1999
of tumors by neuroimaging is difficult. Cho reflects membrane turnover, correlates with malignancy in astrocytic tumors, and forms high peaks in meningioma. The most common proton spectrum found in meningiomas is a high Cho peak with low or absent NAA and Cr and variable amounts of lactate. Most important, an unusually high ratio of Ala to Cr has been found in meningiomas because of the high Ala and low Cr content, and this is a relatively specific finding for meningioma. Alanine is seen as doublet centered at 1.47 ppm and inverts on the long-TE sequence.
Reference- AJNR Am J Neuroradiol 20:882–885, May 1999
Labels: medical imaging, Meningioma, MRI, MRS, Teleradiology
posted by Sumer Sethi @ Saturday, April 26, 2008
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For more information on topics such as this please join us at our 12th Annual Clinical Magnetic Resonance Society Meeting, June 26 - 29, 2008 at Disney's Board Walk Resort in Lake Buena Vista, Fl.
www.cmrs.org
813-806-1080
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