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CADASIL-Radiology

A familial form of vascular dementia affecting younger patients is currently very topical: CADASIL (cerebral autosomal dominant arteriopathy, subcortical infarcts and leucoencephalopathy)

  • Clinical features: Stroke and migraine as well as dementia are common clinical features. 
  • The gene is known, but sporadic mutations occur. 
  • Radiology:On MRI there is usually striking confluent ischaemic damage throughout the cerebral white matter (including temporal lobes, often spared in arteriosclerotic disease) and basal ganglia. 
CADASIL-Radiology Reviewed by Sumer Sethi on Monday, July 29, 2013 Rating: 5

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