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Potential Treatment for Alzheimer Disease

Burgess et al present intriguing results of repetitive transient opening of the blood-brain barrier (BBB) in a transgenic mouse model of advanced Alzheimer disease (AD). The results underscore the potential of using magnetic resonance (MR) imaging–guided focused ultrasound and microbubble ultrasonography (US) contrast agents for the disruption of the BBB as a potential long-term therapy to reduce amyloid plaque burden and improve cognitive performance.

Science to Practice: Opening the Blood-Brain Barrier with Focused Ultrasound—A Potential Treatment for Alzheimer Disease? Ferenc A. Jolesz. Radiology 2014 273:3 , 631-633 
Potential Treatment for Alzheimer Disease Reviewed by Sumer Sethi on Tuesday, November 25, 2014 Rating: 5

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