Pigmented Villonodular Synovitis Ankle

Here is a case of PVNS. 32 years old female with gradual onset ankle swelling. No local manifestation suggestive of arthritis. She is not known to be rheumatoid arthritis patient.  Case submitted by: Dr. Wael Nemattalla, MD, Radiodiagnosis from  Egypt. 

Pigmented villonodular synovitis (PVNS) is relatively uncommon. The disorder results in increased proliferation of synovium causing villous or nodular changes of synovial-lined joints, bursae and tendon sheaths. PVNS should be considered in athletically active patients with persistent lateral ankle pain and swelling, particularly if bone erosions are visible on plain radiographs.