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NEJM- osteochondromas after body irradiation

An article in this weeks NEJM entitled Osteochondromas after Total-Body Irradiation. N Engl J Med 2011; 364:687-688. By Marisa K. Matthys, B.S., Jane E. Benson, M.D. from Johns Hopkins University, Baltimore, MD  reports-
" The occurrence of osteochondroma after total-body irradiation has been increasingly reported in the literature and is probably the result of a prolonged duration of epiphyseal opening caused by damage to bone and cartilage at the epiphysis. Analyses have shown that the age at the time of transplantation is an independent risk factor for osteochondroma, with most reports involving children under the age of 5 years. "
NEJM- osteochondromas after body irradiation Reviewed by Sumer Sethi on Thursday, February 17, 2011 Rating: 5

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