Wednesday, July 18, 2007

Maganese in brain on MRI

"Manganese (Mn) accumulation in the brain is detected as symmetrical high signal intensity in the globus pallidi on T1-weighted MR images without an abnormal signal on T2-weighted images. Mn accuulation in the brain is due to acquired or congenital diseases of the abdomen including hepatic cirrhosis with a portosystemic shunt, congenital biliary atresia, primary biliary cirrhosis, congenital intrahepatic portosystemic shunt without liver dysfunction, Rendu-Osler-Weber syndrome with a diffuse intrahepatic portosystemic shunt, and patent ductus venosus. Other causes of Mn accumulation in the brain are Mn overload from total parenteral nutrition and welding-related Mn intoxication."

Neuroradiology 2007 Jul 12; [Epub ahead of print]

1 comment:

Anonymous said...

I was subjected to high levels of Manganese due to emmissions from a plant less than 1/4 mile from my home. I was told to get a blood test for exact levels. Should I insist on the MRI? I am suffering neurological problems including memory loss and cognitive problems. Along with some other symptoms.

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